DNA Pharmacogenetics Test

Name: DNA Pharmacogenetics Test
Brand: Homed-IQ
Price: 269.0 EUR
Availability: OutOfStock
Rating: 4.6 (1166 reviews)

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Medications can affect people differently depending on their genetic makeup. The Pharmacogenetics Test analyses important genetic variations that influence how your body processes and responds to certain medications. With a simple at-home DNA sample, this test helps you gain insight into how your genes may impact medication effectiveness, dosage requirements, and the likelihood of side effects.

The results can support more personalised healthcare decisions together with your doctor or healthcare provider. Whether you are currently using medication, have experienced side effects in the past, or want to better understand your body’s response to treatment, this test provides valuable insights into your genetic profile.

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ABCG2 – Helps transport substances and medicines out of cells. Variants may affect the body’s handling of gout medications such as allopurinol and certain cholesterol-lowering or cancer medicines.
COMT – Involved in breaking down neurotransmitters such as dopamine and adrenaline. It may influence response to psychiatric medications, pain medication, and treatments affecting the nervous system.
CYP1A2 – A liver enzyme responsible for metabolising caffeine and several medications. It is particularly relevant for caffeine sensitivity, antipsychotics, and some antidepressants.
CYP2B6 – Helps process a range of medicines in the liver. Variants can influence response to medications used in neurology, anaesthesia, smoking cessation, and infectious disease treatment.
CYP2C9 – Important for breaking down commonly used medications. It significantly impacts blood thinners such as warfarin, certain painkillers (NSAIDs), and some diabetes medications.
CYP2C19 – Influences how effectively the body processes several widely prescribed medicines. It is especially relevant for antidepressants, proton pump inhibitors, and antiplatelet drugs such as clopidogrel.
CYP2D6 – One of the most clinically important pharmacogenetic genes. It affects the metabolism of many antidepressants, opioids, beta blockers, and psychiatric medications.
CYP3A4 – A major enzyme involved in metabolising a large proportion of all prescription medicines. It impacts many medication groups including statins, immunosuppressants, antibiotics, and cardiovascular drugs.
CYP3A5 – Closely related to CYP3A4 and also involved in medicine metabolism. It is particularly important for immunosuppressive medicines such as tacrolimus.
DPYD – Helps break down fluoropyrimidine chemotherapy drugs. Variants can increase the risk of severe toxicity from medications such as fluorouracil (5-FU) and capecitabine.
G6PD – Protects red blood cells from oxidative damage. Certain variants can increase the risk of red blood cell breakdown when using specific antibiotics, antimalarials, or other medicines.
HLA-B*1502 – An immune-related gene associated with severe hypersensitivity reactions. It is most relevant for anti-epileptic medicines such as carbamazepine.
HLA-B*5701 – Helps predict risk for serious immune-mediated drug reactions. It is especially important before treatment with abacavir and some other medications.
HLA-A*3101 – Linked to increased risk of skin and hypersensitivity reactions to certain medicines. It is mainly associated with carbamazepine treatment.
MTHFR677 – Plays a role in folate metabolism and methylation processes. Variants may influence folate handling and response to a small number of medicines, including methotrexate.
NUDT15 – Helps the body process thiopurine medications safely. Variants can increase sensitivity to azathioprine, mercaptopurine, and related medicines.
SLCO1B1 – Responsible for transporting certain medicines into the liver. It is most strongly linked to statin metabolism and risk of statin-related muscle side effects.
TPMT – Helps break down thiopurine medications. Reduced TPMT activity can increase the risk of toxicity from azathioprine, mercaptopurine, and thioguanine.
UGT1A1 – Involved in the breakdown and elimination of substances through the liver. It is especially relevant for irinotecan chemotherapy and the HIV medicine atazanavir.
VKORC1 – Plays an important role in vitamin K metabolism and blood clotting. Variants strongly influence sensitivity to blood thinners such as warfarin and acenocoumarol.

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DNA Pharmacogenetics Test

€269,00

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Häufig gestellte Fragen

What is a pharmacogenetics test?

A pharmacogenetics test analyses specific genes involved in how your body processes medications. The results can help predict whether certain medicines may work normally, less effectively, or cause an increased risk of side effects.

How can my DNA affect medication?

Your genes influence how quickly your body breaks down and processes medicines. Some people metabolise medications very quickly, while others process them more slowly, which can affect effectiveness, dosing, and the likelihood of side effects.

Who can benefit from a pharmacogenetics test?

This test may be helpful for people who:

Experience side effects from medication
Feel their medication is not working as expected
Use multiple medications
Want proactive insight before starting treatment
Have a history of unusual medication responses

It can also be valuable for doctors and pharmacists when choosing medication or adjusting dosage.

Can this test tell me which medication is best for me?

The test does not directly prescribe medication, but it can provide valuable information about how your body may respond to certain medicines. Your doctor or pharmacist can use this information to support treatment decisions.

Do I need to stop my medication before taking the test?

No. The test analyses your DNA, which does not change based on current medication use. You can usually continue taking your medication as prescribed unless advised otherwise by your healthcare provider.

Will my DNA change over time?

No. Your pharmacogenetic profile is lifelong and does not change over time. In most cases, this test only needs to be performed once.

Can I share my results with my doctor or pharmacy?

Yes. The report is designed to be shared with healthcare professionals and may help support medication reviews, dosing decisions, and treatment discussions. Some pharmacies can also register pharmacogenetic results in your medication file.

Does a genetic variant always mean a medicine is unsafe?

No. A genetic variant does not automatically mean a medication is dangerous or unsuitable. In many cases, the information may simply help guide dosage adjustments or closer monitoring.

Is this test useful even if I’m healthy?

Yes. Many people choose pharmacogenetic testing proactively so they already have their genetic medication profile available if they need medication in the future.

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